A New Prenylflavonoid Isolated from Propolis Collected in the Solomon Islands

Saori INUI; Yuko SHIMAMURA; Shuichi MASUDA; Kenichi SHIRAFUJI; Reuben T. MOLI; Shigenori KUMAZAWA

doi:10.1271/bbb.120021

Organic Chemistry Notes

A New Prenylflavonoid Isolated from Propolis Collected in the Solomon Islands

Saori INUI, Yuko SHIMAMURA, Shuichi MASUDA, Kenichi SHIRAFUJI, Reuben T. MOLI, Shigenori KUMAZAWA

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Keywords: propolis, The Solomon Islands, prenylflavonoid, solophenol A, radical-scavenging activity

JOURNAL FREE ACCESS

2012 Volume 76 Issue 5 Pages 1038-1040

DOI https://doi.org/10.1271/bbb.120021

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Abstract

The new prenylflavonoid, solophenol A (1), together with three known compounds, bonannione A (2), sophoraflavanone A (3) and (2S)-5,7-dihydroxy-4'-methoxy-8-prenylflavanone (4), were isolated from propolis collected from Malaita Island in The Solomon Islands. The structure of each compound was determined by spectroscopic methods, including mass spectrometry and 2D NMR. Compound 1 exhibited potent 2,2-diphenyl-1-picrylhydrazyl radical-scavenging activity.

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