Identification of a Nitric Oxide Generation-Stimulative Principle in Scutellariae radix

Ziyang CHEN; Kenichi NIHEI; Hideyuki TANAKA; Yasushi UDA; Yukihito KABUYAMA

doi:10.1271/bbb.120800

Analytical Chemistry Note

Identification of a Nitric Oxide Generation-Stimulative Principle in Scutellariae radix

Ziyang CHEN, Kenichi NIHEI, Hideyuki TANAKA, Yasushi UDA, Yukihito KABUYAMA

著者情報

キーワード: Scutellariae radix, baicalin, endothelial nitric oxide, human umbilical vein endothelial cells

ジャーナルフリー

2013 年 77 巻 3 号 p. 657-659

DOI https://doi.org/10.1271/bbb.120800

View "Advance Publication" version (March 7, 2013).

詳細

抄録

Scutellariae radix (SR, from the roots of Scutellaria baicalensis Georgi) is thought to regulate blood pressure. In this study, HPLC-based purification coupled with MS, NMR analysis revealed that baicalin, a major flavone in SR, stimulates endothelial NO generation, suggesting its potential as an ingredient in medicinal food and beverage to treat hypertension.

責任著者(Corresponding author)

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