Xylomexicanins C and D, New Mexicanolide-Type Limonoids from Xylocarpus granatum

Yi-Bing WU; Zhi-Yu NI; Chang-Hong HUO; Jian SU; Mei DONG; Françoise SAURIOL; Qing-Wen SHI; Yu-Cheng GU; Hiromasa KIYOTA

doi:10.1271/bbb.120815

Organic Chemistry Regular Papers

Xylomexicanins C and D, New Mexicanolide-Type Limonoids from Xylocarpus granatum

Yi-Bing WU, Zhi-Yu NI, Chang-Hong HUO, Jian SU, Mei DONG, Françoise SAURIOL, Qing-Wen SHI, Yu-Cheng GU, Hiromasa KIYOTA

著者情報

Yi-Bing WU
School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University
Zhi-Yu NI
Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine
Chang-Hong HUO
School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University
Jian SU
Hebei Provincial Institute for Food and Drug Control
Mei DONG
Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine
Françoise SAURIOL
Department of Chemistry, Queen's University
Qing-Wen SHI
School of Pharmaceutical Sciences, Hebei Key Laboratory of Forensic Medicine, Hebei Medical University
Yu-Cheng GU
Syngenta Jealott's Hill International Research Centre
Hiromasa KIYOTA
Graduate School of Agricultural Science, Tohoku University

キーワード: NMR, Xylocarpus granatum, limonoid, mexicanolide, structural elucidation

ジャーナルフリー

2013 年 77 巻 4 号 p. 736-740

DOI https://doi.org/10.1271/bbb.120815

View "Advance Publication" version (April 7, 2013).

詳細

抄録

Two new limonoids, named xylomexicanins C and D, were isolated from a dichloromethane extract of the seeds of Xylocarpus granatum cultivated in Hainan, China, and their structures were elucidated on the basis of one- and two-dimensional NMR (including ¹H, ¹³C-NMR, DEPT, ¹H-¹H COSY, HSQC, HMBC, and NOESY) and confirmed by high-resolution mass spectrometry. Xylomexicanin C exhibited antiproliferative activity against human breast carcinoma cells (KT).

責任著者(Corresponding author)

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