Anti-Inflammatory and Antioxidative Effects of a Methanol Extract from Bulbs of Scilla scilloides

Shin YASUDA; Youichirou NISHIDA; Kensuke WADA; Daisuke AKIYAMA; Daiki TOYOHISA; Toshiharu TANAKA; Keiji IGOSHI; Masateru ONO

doi:10.1271/bbb.120906

Food & Nutrition Science Notes

Anti-Inflammatory and Antioxidative Effects of a Methanol Extract from Bulbs of Scilla scilloides

Shin YASUDA, Youichirou NISHIDA, Kensuke WADA, Daisuke AKIYAMA, Daiki TOYOHISA, Toshiharu TANAKA, Keiji IGOSHI, Masateru ONO

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Keywords: Scilla scilloides, lipoxygenase, hyaluronidase, inflammation, antioxidation

JOURNAL FREE ACCESS

2013 Volume 77 Issue 7 Pages 1569-1571

DOI https://doi.org/10.1271/bbb.120906

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Abstract

The extract from bulbs of Scilla scilloides exhibited inhibitory effects in lipoxygenase and hyaluronidase assays and various oxidation models in vitro. Incubating the cells in the presence of this extract ameliorated t-butyl hydroperoxide-induced cytotoxicity from 27% to 57% in a macrophage model. The results may indicate the potential role of S. scilloides for its anti-inflammatory and antioxidative effects.

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