The Urinary Excretory Ratio of Nicotinamide Catabolites Was Associated with the Conversion Ratio of Tryptophan to Nicotinamide in Growing Rats Fed a Niacin-Free 20% Casein Diet

Katsumi SHIBATA; Eri IMAI; Mitsue SANO; Tsutomu FUKUWATARI

doi:10.1271/bbb.110564

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The Urinary Excretory Ratio of Nicotinamide Catabolites Was Associated with the Conversion Ratio of Tryptophan to Nicotinamide in Growing Rats Fed a Niacin-Free 20% Casein Diet

Katsumi SHIBATA, Eri IMAI, Mitsue SANO, Tsutomu FUKUWATARI

著者情報

キーワード: N¹-methylnicotinamide, N¹-methyl-2-pyridone-5-carboxamide, N¹-methyl-4-pyridone-3-carboxamide, tryptophan-nicotinamide conversion ratio

ジャーナルフリー早期公開

論文ID: 110564

DOI https://doi.org/10.1271/bbb.110564

この記事には本公開記事があります。

The final version of this article is now available: Vol. 76 (2012) , No. 1 p.186

詳細

抄録

Weaning rats were fed a niacin-free 20% casein diet. Twenty-four-h-urine samples were collected, and nicotinamide and its catabolites were measured. A correlation was found between the urinary excretory ratio of nicotinamide catabolites (N¹-methyl-2-pyridone-5-carboxamide + N¹-methyl-4-pyridone-3-carboxamide)/N¹-methylnicotinamide and the tryptophan-nicotinamide conversion ratio during growing period of the rats. This indicates the possibility that the conversion ratio can be deduced from the excretory ratio.

責任著者(Corresponding author)

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