Serum Cholesterol Reduction by Feeding a High-Cholesterol Diet Containing a Lower-Molecular-Weight Polyphenol Fraction from Peanut Skin

Tomoko TAMURA; Naoko INOUE; Akiko SHIMIZU-IBUKA; Miki TADAISHI; Toshichika TAKITA; Soichi ARAI; Kiyoshi MURA

doi:10.1271/bbb.110866

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引用する場合も本公開記事を引用してください。

Serum Cholesterol Reduction by Feeding a High-Cholesterol Diet Containing a Lower-Molecular-Weight Polyphenol Fraction from Peanut Skin

Tomoko TAMURA, Naoko INOUE, Akiko SHIMIZU-IBUKA, Miki TADAISHI, Toshichika TAKITA, Soichi ARAI, Kiyoshi MURA

著者情報

キーワード: peanut skin, polyphenol, cholesterol, micelle solubility, bile acid

ジャーナルフリー早期公開

論文ID: 110866

DOI https://doi.org/10.1271/bbb.110866

この記事には本公開記事があります。

The final version of this article is now available: Vol. 76 (2012) , No. 4 p.834

詳細

抄録

Feeding a high-cholesterol diet with a water-soluble peanut skin polyphenol fraction to rats reduced their plasma cholesterol level, with an increase in fecal cholesterol excretion. The hypocholesterolemic effect was greater with the lower-molecular-weight rather than higher-molecular-weight polyphenol fraction. This effect was possibly due to some oligomeric polyphenols which reduced the solubility of dietary cholesterol in intestinal bile acid-emulsified micelles.

責任著者(Corresponding author)

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