Screening and Identification of Disaccharides with Insulin Mimetic Activity against L6 Cells

Kazuaki YAMASAKI; Ryogo HISHIKI; Eisuke KATO; Jun KAWABATA

doi:10.1271/bbb.110884

This article has now been updated. Please use the final version.

Screening and Identification of Disaccharides with Insulin Mimetic Activity against L6 Cells

Kazuaki YAMASAKI, Ryogo HISHIKI, Eisuke KATO, Jun KAWABATA

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Keywords: insulin mimetic, disaccharide, diabetes mellitus, glucose uptake, L6 cell

JOURNAL FREE ACCESS Advance online publication

Article ID: 110884

DOI https://doi.org/10.1271/bbb.110884

The final version of this article is now available: Vol. 76 (2012) , No. 4 p.841

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Abstract

Insulin mimetics are considered as prospective anti-diabetic agents, and the disaccharide, neohesperidose, has been found to show insulin mimetic activity against L6 cells. We screened several other disaccharides for their insulin mimetic activity and identified three new insulin mimetic disaccharides.

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