Orally and Topically Administered Sparassis crispa (Hanabiratake) Improved Healing of Skin Wounds in Mice with Streptozotocin-Induced Diabetes

Kyosuke YAMAMOTO; Takashi KIMURA

doi:10.1271/bbb.121016

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Orally and Topically Administered Sparassis crispa (Hanabiratake) Improved Healing of Skin Wounds in Mice with Streptozotocin-Induced Diabetes

Kyosuke YAMAMOTO, Takashi KIMURA

著者情報

キーワード: Sparassis crispa (hanabiratake), β-glucan, wound healing

ジャーナルフリー早期公開

論文ID: 121016

DOI https://doi.org/10.1271/bbb.121016

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013) , No. 6 p.1303

詳細

抄録

Sparassis crispa (SC) contains significant concentrations of β-glucan, which can accelerate wound healing, but the dose dependence for oral administration and the effects of topical administration are unknown. In streptozotocin-induced diabetic mice, dietary SC promoted dose-dependent effective wound healing. Similar wound-healing activity was observed when purified SC β-glucan was topically applied to wounds of diabetic mice.

責任著者(Corresponding author)

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