Changes in NAD Content Induced by Nicotinic Acid-Related Compounds in K562 Cells during Differentiation

Chieri IDA; Shin OGATA

doi:10.1271/bbb.130131

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Changes in NAD Content Induced by Nicotinic Acid-Related Compounds in K562 Cells during Differentiation

Chieri IDA, Shin OGATA

著者情報

キーワード: nicotinamide adenine dinucleotide (NAD), nicotinic acid, isonicotinic acid, cell differentiation, K562

ジャーナルフリー早期公開

論文ID: 130131

DOI https://doi.org/10.1271/bbb.130131

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013) , No. 7 p.1583

詳細

抄録

Two nicotinic acid-related compounds were found to induce erythroid differentiation in K562 cells. We investigated the changes in nicotinamide adenine dinucleotide (NAD) content induced by nicotinic acid-related compounds during differentiation. The NAD content was reduced by a treatment with nicotinic acid and isonicotinic acid. These results provide important clues toward elucidating the erythroid differentiation mechanism.

責任著者(Corresponding author)

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