Regulation of the Basolateral Na+, K+-ATPase in the Activation of Electrogenic Na+ Absorption Induced by Isoproterenol in the Rat Distal Colon

Yo TSUCHIYA; Yuichi SUZUKI

doi:10.1271/bbb.130140

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Regulation of the Basolateral Na⁺, K⁺-ATPase in the Activation of Electrogenic Na⁺ Absorption Induced by Isoproterenol in the Rat Distal Colon

Yo TSUCHIYA, Yuichi SUZUKI

著者情報

キーワード: electrogenic Na⁺ absorption, colon, Na⁺, K⁺-ATPase, cAMP

ジャーナルフリー早期公開

論文ID: 130140

DOI https://doi.org/10.1271/bbb.130140

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013), No. 9 pp. 1955-1957

詳細

抄録

We investigated the effects of cAMP on the basolateral Na⁺, K⁺-ATPase and apical amiloride-sensitive Na⁺ channel in the rat distal colon. Under mucosal treatment with nystatin, isoproterenol and forskolin increased the basolateral Na⁺ pump current. Under serosal treatment with ouabain, both agents slightly increased the amiloride-sensitive Na current, but not to a significant level. We concluded that cAMP activates the basolateral Na⁺, K⁺-ATPase in the rat distal colon.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）