Octaphlorethol A Inhibits the CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase and NF-κB Pathways

Zahid MANZOOR; Vivek Bhakta MATHEMA; Doobyeong CHAE; Hee-Kyoung KANG; Eun-Sook YOO; You-Jin JEON; Young-Sang KOH

doi:10.1271/bbb.130299

この記事には本公開記事があります。本公開記事を参照してください。
引用する場合も本公開記事を引用してください。

Octaphlorethol A Inhibits the CpG-Induced Inflammatory Response by Attenuating the Mitogen-Activated Protein Kinase and NF-κB Pathways

Zahid MANZOOR, Vivek Bhakta MATHEMA, Doobyeong CHAE, Hee-Kyoung KANG, Eun-Sook YOO, You-Jin JEON, Young-Sang KOH

著者情報

キーワード: octaphlorethol A, pro-inflammatory cytokines, mitogen-activated protein kinase, NF-κB

ジャーナルフリー早期公開

論文ID: 130299

DOI https://doi.org/10.1271/bbb.130299

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013), No. 9 pp. 1970-1972

詳細

抄録

Octaphlorethol A is a phenolic compound isolated from the marine alga Ishige foliacea. In the present study, we investigated the anti-inflammatory activity of octaphlorethol A in CpG-stimulated primary murine bone marrow-derived macrophages and dendritic cells. It exhibited anti-inflammatory activity by regulating the mitogen-activated protein kinase and NF-κB pathways.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）