Activation of the hTAS2R14 Human Bitter-Taste Receptor by (−)-Epigallocatechin Gallate and (−)-Epicatechin Gallate

Toyomi YAMAZAKI; Masataka NARUKAWA; Mineko MOCHIZUKI; Takumi MISAKA; Tatsuo WATANABE

doi:10.1271/bbb.130329

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Activation of the hTAS2R14 Human Bitter-Taste Receptor by (−)-Epigallocatechin Gallate and (−)-Epicatechin Gallate

Toyomi YAMAZAKI, Masataka NARUKAWA, Mineko MOCHIZUKI, Takumi MISAKA, Tatsuo WATANABE

著者情報

キーワード: green tea, catechin, bitter taste, bitter taste receptor, hTAS2R14

ジャーナルフリー早期公開

論文ID: 130329

DOI https://doi.org/10.1271/bbb.130329

この記事には本公開記事があります。

The final version of this article is now available: Vol. 77 (2013), No. 9 pp. 1981-1983

詳細

抄録

Tea catechins have strong bitterness and influence the taste of tea. Among the 25 human bitter-taste receptors (TAS2Rs), we found that hTAS2R14 responded to catechins, in addition to hTAS2R39, a known catechin receptor. Although hTAS2R14 responded to (−)-epicatechin gallate and (−)-epigallocatechin gallate, it did not respond to (−)-epicatechin and (−)-epigallocatechin.

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