Activation of the hTAS2R14 Human Bitter-Taste Receptor by (−)-Epigallocatechin Gallate and (−)-Epicatechin Gallate

Toyomi YAMAZAKI; Masataka NARUKAWA; Mineko MOCHIZUKI; Takumi MISAKA; Tatsuo WATANABE

doi:10.1271/bbb.130329

Food & Nutrition Science Notes

Activation of the hTAS2R14 Human Bitter-Taste Receptor by (−)-Epigallocatechin Gallate and (−)-Epicatechin Gallate

Toyomi YAMAZAKI, Masataka NARUKAWA, Mineko MOCHIZUKI, Takumi MISAKA, Tatsuo WATANABE

著者情報

キーワード: green tea, catechin, bitter taste, bitter taste receptor, hTAS2R14

ジャーナルフリー

2013 年 77 巻 9 号 p. 1981-1983

DOI https://doi.org/10.1271/bbb.130329

View "Advance Publication" version (September 7, 2013).

詳細

抄録

Tea catechins have strong bitterness and influence the taste of tea. Among the 25 human bitter-taste receptors (TAS2Rs), we found that hTAS2R14 responded to catechins, in addition to hTAS2R39, a known catechin receptor. Although hTAS2R14 responded to (−)-epicatechin gallate and (−)-epigallocatechin gallate, it did not respond to (−)-epicatechin and (−)-epigallocatechin.

責任著者(Corresponding author)

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