Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip, Brassica, campestris L.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice

Abstract

Isorhamnetin 3-O-glucoside, which was contained together with isorhamnetin 3,7-di-O-glucoside in atsumi-kabu leaves, suppressed increases in the plasma ALT and AST activities of mice with liver injury induced by the injection of carbon tetrachloride, but no suppression by isorhamnetin 3,7-di-O-glucoside was apparent. This result indicates that the release of glucose at the 7-position in isorhamnetin 3,7-di-O-glucoside was very important to mitigating liver injury.