Accumulation of the Bioactive Peptides, Novokinin, LPYPR and Rubiscolin, in Seeds of Genetically Modified Soybean

Keito NISHIZAWA; Akiko KITA; Chieko DOI; Yuko YAMADA; Kousaku OHINATA; Masaaki YOSHIKAWA; Masao ISHIMOTO

doi:10.1271/bbb.80468

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Accumulation of the Bioactive Peptides, Novokinin, LPYPR and Rubiscolin, in Seeds of Genetically Modified Soybean

Keito NISHIZAWA, Akiko KITA, Chieko DOI, Yuko YAMADA, Kousaku OHINATA, Masaaki YOSHIKAWA, Masao ISHIMOTO

著者情報

キーワード: bioactive peptide, bioreactor, dietetic therapy, molecular farming, transgenic soybean

ジャーナルフリー早期公開

論文ID: 80468

DOI https://doi.org/10.1271/bbb.80468

この記事には本公開記事があります。

The final version of this article is now available: Vol. 72 (2008) , No. 12 p.3301

詳細

抄録

Novokinin (RPLKPW), LPYPR, and rubiscolin (YPLDLF) are bioactive peptides with respective hypotensive, hypocholesterolemic, and memory-enhancing activities. We generated transgenic soybean lines that expressed modified forms of the α′ subunit of seed storage protein β-conglycinin containing tandem repeats of these bioactive peptides. The modified α′ subunits constituted up to 0.2% of extracted proteins from the transgenic seeds.

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