New Cytotoxic Phenolic Derivatives from Matured Fruits of Magnolia denudata

Toshiro NOSHITA; Hiromasa KIYOTA; Yumi KIDACHI; Kazuo RYOYAMA; Shinji FUNAYAMA; Ken HANADA; Tetsuya MURAYAMA

doi:10.1271/bbb.80597

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New Cytotoxic Phenolic Derivatives from Matured Fruits of Magnolia denudata

Toshiro NOSHITA, Hiromasa KIYOTA, Yumi KIDACHI, Kazuo RYOYAMA, Shinji FUNAYAMA, Ken HANADA, Tetsuya MURAYAMA

著者情報

キーワード: Magnolia denudata, benzofuranone, denudalide, denudaquinol, cytotoxic metabolite

ジャーナルフリー早期公開

論文ID: 80597

DOI https://doi.org/10.1271/bbb.80597

この記事には本公開記事があります。

The final version of this article is now available: Vol. 73 (2009) , No. 3 p.726

詳細

抄録

Magnolia species are widely cultivated in Japan as garden plants, and have been found to contain various compounds, including alkaloids, terpenoids, lignans, and neolignans. The constituents of the mature fruits of M. denudata were investigated, and two new phenolic derivatives, named denudalide and denudaquinol, were isolated and characterized, together with a known neolignan compound (denudatin A). Denudalide and denudaquinol showed cytotoxicity against the SFME and r/mHM-SFME-1 cell lines.

責任著者(Corresponding author)

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