抄録
During investigations conducted on the mode of degradation of ribonucleic acid by Microorganisms, it was found that one strain of Penicillium produces nucleoside-5'-monophosphates from ribonucleic acid. Identification of these nucleoside-5'-monophosphates was carried out by means of chromatography on anion exchange column, ultraviolet spectrophotometry, paper electrophoresis, and characteristic color reactions using orcinol, carbazole, and rosaniline. It is suggested that this strain contains 5'-phosphodiesterase (or 5'-phosphodiesterase system) which cleaves all of the 5'-phosphodiester linkages in ribonucleic acid thus giving rise to nucleoside-5'-monophosphates. It is a point of interest in this study to indicate the presence of 5'-phosphodiesterase for the first time in a common microorganism, as 5'-phosphodiesterase has been recognized only in somewhat particular materials such as snake venom.
