Studies on the Organophosphorus Insecticides

Part I. Synthesis and Toxicity of Phosphates Containing Vinyl Radical

Abstract

Many phosphates containing vinyl radical such as Phosdrin¹⁾ were prepared in order to study the correlation between structure and toxicity. From the results obtained it seems certain that in regard of toxicity, it is the carboalcoxy radical rather than the vinyl radical that is necessary and furthermore the toxicity is connected with the atom or the radical linked with the vinyl radical. As a results of these studies, some new toxic phosphates were synthesized.