Polarographic Studies on Sarkomycin

Part IV. Polarography of Isoniazid and Sarkomycin-isoniazid Derivative. 2

抄録

Quantitative analyses of sarkomycin-isoniazid derivative (SK-INH), isoniazid (INH) and their mixture are discussed. The diffusion current of SK-INH gives a linear relationship with the concentration only in the same lot, but this calibration curve cannot be applied for samples of other lots. Increase in the diffusion currents of the first and the second wave in a mixture of SK-INH and INH yields straight lines against the added INH, which coincide well with the calibration curve of INH. Relation between diffusion currents of the first and the second wave and nitrogen contents, obtained by a lot of SK-INH, cannot be used for other lots of sample. Ratios of the diffusion currents of these waves show different values in each sample, which are larger than in INH.