Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Studies on Kojic Acid and its Related γ-Pyrone Componds
Part VIII. Synthesis of Comenic Aicd form Kojic Acid (Synthesis of Maltol (2))
Itsuo ICHIMOTOKichitaro FUJIIFumio SEKIDOSeiichi NONOMURAChuji TATSUMI
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1965 年 29 巻 2 号 p. 99-103

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An extensive study has been made on the oxidation of the hydroxymethyl group of kojic adid. Benzyl or methyl ether of kojic acid was easily oxidized to the corresponding comenic acid ether by the action of microorganism; the comenic acid ethers were obtained nearly quantitatively from the replacement culture in phosphate buffer solution (pH 7.2). In addition, hydrogenolysis of the comenic acid ether has been studied. The use of pal-ladium catalyst such as colloidal-Pd or Pd-BaSO4 gave a comenic acid in good yield.
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© Japan Society for Bioscience, Biotechnology, and Agrochemistry
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