抄録
A rod-shaped and Gram-positive anaerobic S-equol-producing intestinal bacterium, TM-30, was isolated from the feces of a healthy human. The 16S rRNA partial sequence of strain TM-30 exhibited 99% identity to that of Slackia sp. NATTS. TM-30 produced S-equol from daidzein. The in vitro incubation of β-estradiol with TM-30 yielded estrone, and incubation of estrone with TM-30 produced β-estradiol. The estrone producing activity was higher than the β-estradiol producing activity. The results presented herein demonstrate that the S-equol-producing human intestinal bacterium, TM-30, likely plays a role in estrone and β-estradiol metabolism in vitro.
