Studies on Fish-killing Components of Callicarpa candicans

Part I. Isolation of Callicarpone and its Toxicity to Fish

Abstract

A fish-killing component, which was named callicarpone, C₂₀H₂₈O₄, m. p. 111°C, [α]^23°D-188° (chloroform) was isolated from the leaf of Callicarpa candicans and was found to have conjugated carbonyl groups, double bond and one hydroxyl group. The toxicity to fish was evaluated to be as strong as rotenone and ten times stronger than sodium pent achlorophenoxide.