抄録
Relation between biotin and oleic acid was studied using a biotin-requiring organism accumulating L-glutamic acid and its blocked mutants lacking the biosynthetic system of biotin or/and oleic acid. The results support the following considerations. Biotin is not formed from oleic acid and does not substantially affect the growth of L-glutamic acidaccumulating bacteria and their productivity of L-glutamic acid.
Consequently, biotin serves only for the synthesis of fatty acids in the present organisms. The essential factor for their growth and metabolism is an unsaturated fatty acid like oleic acid and not biotin. And also, saturated fatty acids have substantially no relation with their growth and metabolism like accumulation of L-glutamic acid.
