Synthese von 1, 3, 5-Triazinen aus Aminosäure-Derivaten. (III)

Abstract

Amino acid esters as well as peptideesters reacted directly, without addition of DCC, with dimethylbiguanide to give triazine-derivatives. The yields of the triazine-derivatives were fairly good and the racemization did not occur during the reactions. The carbobenzoxy group of N-end was removed by treatment with 25% HBr at room temp. without decomposition of the triazine-ring formed at the C-terminal.