Syntheses and PMR Studies of 1, 2, 3, 4, 5-Pentachlorocyclohexane Isomers, Tetrachloromonomethoxycyclohexane Isomers and Related Compounds

Abstract

Two diastereomers of 1, 2, 3, 4, 5-pentachlorocyclohexane⁺⁺ and two diastereomers of tetrachloromonomethoxycyclohexane were synthesized stepwise from diastereomers of 3, 4, 5-trichlorocyclohexene, which had been derived from the DL-(36/45)-, DL-(34/56)- and (346/5)-isomers of 3, 4, 5, 6-tetrachlorocyclohexene⁺⁺ (α-, β- and γ-BTC, respectively) by selective reduction with LiAlH₄. The configurations of all the products and intermediary trichlorocyclohexene isomers were determined by PMR studies.