Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Identification and Some Culture Conditions of 2'-Amino-2'-deoxyguanosine-producing Enterobacter cloacae
Toshihide NAKANISHIFusao TOMITATakeo SUZUKI
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1977 年 41 巻 2 号 p. 287-291

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A bacterium KY 3071 that was found to produce a new aminonucleoside antibiotics, 2'-amino-2'-deoxyguanosine (2 AG), was identified as Enterobacter cloacae KY 3071.
Amount of dipotassium phosphate and ammonium sulfate affected 2 AG production greatly and their concentration must be 0.2 and 15g/liter for the efficient 2 AG production, respectively.
Addition of purine nucleotides promoted 2 AG production, particularly xanthosine-5'-monophosphate was most effective, and purine nucleosides, on the contrary, inhibited the 2 AG production. The maximum amounts of 2 AG were approximately 0.4g/liter after 24 hr of incubation.
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© Japan Society for Bioscience, Biotechnology, and Agrochemistry
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