Abstract
Di-, tri- and tetra-saccharides containing amino sugar I were newly isolated as amino sugar components from the partial acid hydrolysate of antibiotic K-52B. From methylation analyses and complete hydrolyses of these oligosaccharides, the structures were elucidated as → 1)-Glcp-(4→)-amino sugar I for the disaccharide (amino sugar II); Galp-(1→1)-Glcp-(4→)-amino sugar I for the trisaccharide (amino sugar III); and Araf-(1→4)-Galp-(1→1)-Glcp-(4→)-amino sugar I for the tetrasaccharide (amino sugar IV). From these results and structures of constituent neutral oligosaccharides, the structure of antibiotic K-52B was proposed to be:
Formyl
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Glcp-(1→4)-Galp-(1→4)-Fuc-(1→4)-Glcp-(1→5)-Araf-(1→4)-Galp- (1→1) -Glcp- (4→)-amino sugar I.
