The Synthesis of D-(6R)- and (6S)-(6-²H₁)-Galactose

抄録

D-(6R)- and (6S)-(6-²H₁)-Galactose were regio- and stereospecifically synthesized through photobromination of 1, 6-anhydrogalactose derivatives. The (6S)-compound was prepared in a similar manner to our previous synthesis of D-(6S)-(6-²H₁)-glucose. The inversion to the (6R)-galacto derivatives was performed via (6S)-(6-²H₁)-6-ρ-toluenesulfonyl-l, 2;3, 4-di-O-isopropyridene-α-D-galactose.