Agricultural and Biological Chemistry
Online ISSN : 1881-1280
Print ISSN : 0002-1369
ISSN-L : 0002-1369
Oxidation of Secondary Alcohols to Methylketones by a Gaseous Hydrocarbon Assimilating Mold, Scedosporium sp. A-4
Masayuki ONODERANagahiro OGASAWARA
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1989 年 53 巻 10 号 p. 2673-2677

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Secondary alcohols (C3 to C10) were oxidized to the corresponding methylketones by resting mycelia of Scedosporium sp. A-4 grown on propane, but 3-pentanol and 3-hexanol were not oxidized. The oxidation of 2-propanol to acetone was inhibited by pyrazole, potassium cyanide, sodium azide and Hg2+. Alcohol dehydrogenase activity was found in the cell-free soluble fraction and this activity requires a cofactor, specifically NAD+. The oxidation of both 1-propanol and 2-propanol may be catalyzed by the same alcohol dehydrogenase.
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