Transcriptional Regulation of Meiosis-inducing IME1 and IME2 Genes by GAM Gene Products in Saccharomyces cerevisiae

Abstract

The GAM1, GAM2, and GAM3 genes encode global regulators for transcription in the yeast Saccharomyces cerevisiae. We report here that GAM1 and GAM3 are required for both meiosis and transcriptional activation of meiosis-inducing genes, IME1 and IME2, and that GAM2 is not essential for meiosis but regulates transcription of IME1 and IME2 in positive and negative manners, respectively.