Synthesis of (R)-Callosobruchusic Acid from Methyl (R)-3-Carboxybutanoate

Abstract

(R)-Callosobruchusic acid [(2E, 7R)-3, 7-dimethyl-2-octene-1, 8-dioic acid (1)], the pheromone component of azuki bean weevil (Callosobruchus chinensis), was synthesized from methyl (R)-3-carboxy-butanoate.