Total Synthesis of the Anthelmintic Cyclodepsipeptide, PF1022A
1994 年 58 巻 6 号 p. 1193-1194
詳細
1994 年 58 巻 6 号 p. 1193-1194
The anthelmintic cyclooctadepsipeptide PF1022A and its antipode were synthesized starting from L-Nα-Boc-leucine (for PF1022A), D-Nα-Boc-leucine (for the antipode), L-lactic acid, and L-phenyllactic acid using Mitsunobu reaction and/or the DCC/HOBt method. The antipode had no anthelmintic efficacy.
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