Synthesis and Fungicidal Activities of 4H, 6H-Furo[3, 4-c]isoxazole Derivatives as Potential New Fungicides
1994 年 58 巻 6 号 p. 1191-1192
詳細
1994 年 58 巻 6 号 p. 1191-1192
Furoisoxazoles IIa-r, bicyclic isoxazoles, were designed and synthesized as potential new plant fungicides. The fungicidal activity of each appeared over a broad spectrum of plant pathogens. The preliminary structure-activity relationship for furoisoxazoles II suggests that the methyl and chlorophenyl groups at the 3- and 6-positions, respectively, are essential to their high fungicidal activity. In particular, isoxazoles IIb and IId showed 50% control of RCB and CGM, respectively, at 10ppm.
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