Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Stimulation of Nerve Growth Factor Production by Diterpenoids Isolated from Plants of Euphorbia Species
Kohji YamaguchiDaisuke UemuraTomoko TsujiKiyosi Kondo
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1994 年 58 巻 9 号 p. 1749-1751

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Kansuinin A, ingenol triacetate, and jolkinolide B, diterpenoids isolated from Euphorbia, were found to be potent inducers of nerve growth factor production in L-M cells. Each of these compounds has unique characteristics in the potency of the activity and the range of effective dose. Kansuinin A had the strongest activity, ingenol triacetate had wide-range activity, and jolkinolide B had narrow-range activity.

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