Bioscience and Microflora
Online ISSN : 1349-8355
Print ISSN : 1342-1441
ISSN-L : 1342-1441
Growth Stimulation of Bifidobacteria by a Mixed Culture with Vitamin B12-Producing Klebsiella pneumoniae IFO 13541
Hiroko NODAShoko FUKUDATokumitsu OKAMURAMasahiro OSUGI
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1998 年 17 巻 1 号 p. 49-53

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Klebsiella pneumoniae IFO 13541 is a bacterium which produces vitamin B12. The effect of vitamin B12 on the growth of bifidobacteria was investigated. The addition of vitamin B12 and /or PQQ to the culture medium showed a significant stimulatory effect on the growth of bifidobacteria. The interactions between K. pneumoniae IFO 13541 and Bifidobacterium bifidum A234-4 were investigated in a mixed culture. Under conditions in which both bacteria grew well in pure cultures, K. pneumoniae promoted the growth of B. bifidum.
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