BIOCHEMICAL STUDIES ON INTERMEDIATE METABOLISM OF VITAMINS

I. ON INTERACTION OF VITAMIN B₁ AND SULFHYDRYL GROUP IN PROTEIN MOLECULES

抄録

1. Interaction of vitamin B₁ disulfide and activated sulfhydryl groups in peptides or protein molecules was studied and probable forms of B₁-S-S-glutathione, B₁-S-S-papain, B₁-S-S-eggalbumin and B₁-S-S-serum albumin were observed by paper chromatography as shown in Tables I-VI.
2. Interaction of vitamin B₁ disulfide and pantetheine also seems to produce B₁-S-S-pantetheine.
From these findings, probable reaction in intermediate metabolism of vitamin B₁ is discussed.
The authors wish to express their sincere thanks to Prof. Y. Kuno (Chairman, Committee on Vitamin B Research). The costs of this research have been defrayed from the Department of Education to which the authors' thanks are due.