The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
Stero-Bile Acids and Bile Sterols
XXXIX. Metabolism of Lithocholic Acid
KYUICHIRO OKUDATARO KAZUNO
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1961 年 50 巻 1 号 p. 20-23

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1. Lithocholic acid was incubated res-pectively with liver homogenates of rat and guinea pig.
2. Lithocholic acid was converted mainly to 3α, 6β-dihydroxycholanic acid and partly to chenodeoxycholic acid by rat liver homo-genate.
3. Guinea pig liver homogenate meta-bolized lithocholic acid mainly to chenode-oxycholic acid and partly to an unidentified dihydroxycholanic acid different from 3α, 6β-dihydroxycholanic acid.
The authors wish to thank Mr.-T. Hoshita for synthesis of 3α, 6β-dihydroxycholanic acid.
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© The Japanese Biochemical Society
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