抄録
1. Lithocholic acid was incubated res-pectively with liver homogenates of rat and guinea pig.
2. Lithocholic acid was converted mainly to 3α, 6β-dihydroxycholanic acid and partly to chenodeoxycholic acid by rat liver homo-genate.
3. Guinea pig liver homogenate meta-bolized lithocholic acid mainly to chenode-oxycholic acid and partly to an unidentified dihydroxycholanic acid different from 3α, 6β-dihydroxycholanic acid.
The authors wish to thank Mr.-T. Hoshita for synthesis of 3α, 6β-dihydroxycholanic acid.