Effect of Sample Site on Fatty Acid Composition of Adipose Tissue
1965 年 58 巻 5 号 p. 463-469
詳細
1965 年 58 巻 5 号 p. 463-469
1. Fatty acid composition sof adipose tissue taken from the abdominal wall, mesen-tery, . arm, thigh, hand and foot were examined by gas-liquid chromatography, Fatty acid compositions of the abdominal wall and mesentery were similar, and the compositions of extremities were markedly and persistently different from those of abdominal wall or mesentery.
2. Systematic differences were observed in the contents of saturated and monoenoic acids, and adipose tissue appeared to regulate the ratio of monoenoic acids to saturated acids to adjust its physical property.
3. Determination of iodine value of fat revealed results coincidental with the difference in fatty acid composition of adipose tissue.
4. C20:1 and C22:1 contents were signifi-cantly lower in extremities than in trunk, contrarily to higher contents of C14:1 and C16:1. Clsa took a neutral attitude and its content did not show any meaningful difference through various adipose sites.
5. Fatty acids which revealed marked deviation in their contents were those which could be synthesized in the human body. On the other hand, the C18:2 content was reason-ably constant through various adipose sites. Therefore, the contribution of selective syn-thesis or selectively regulated unsaturation of fatty acids in adipose tissue to the above mentioned deviation of fatty acid composition was considered.
The authors wish to express their thanks to Mrs. M. Yamazaki and Miss T. Hirose for their technical assistance and to Mr. R.E. Kays and Mr. Y. Inada for their help during preparation of the manuscript.
