抄録
The aim of this study is to histologically compare the osseointegration of 2 types of hydroxyapatite (HA)-
coated implants, a JHA implant (Kyocera Medical Ltd, Japan) and a KHA implant (Zimmer Ltd, USA), with the
new bone forming in the space under the lifted membrane (SULM) in a long-term animal experiment of one
stage sinus floor elevation (SFE), without bone substitutes and mechanical loading, using canine frontal sinuses.
Sixteen implants, 8 JHA and 8 KHA were placed in 4 postmenopausal beagles for 3 and 6 months. Histological
observations and histomorphometric measurements were carried out with light-microscopy using hematoxylin
and eosin stained undecalcified specimens. Statistical significant differences were evaluated by one-way
ANOVA.
The new bone formation was observed on a large area of the sinus wall and the implant surface in the
SULM at 3 and 6 months in both groups. Bone implant contact rate with new bone in the SULM was
88.8±10.5% at 3 months and 77.0±7.9% at 6 months in JHA group, and 85.3±7.6 and 87.3±17.9% in KHA group,
respectively. There was no statistical significant difference between the groups. It was concluded that both
types of HA-coated implants have similar properties to promote a superior osseointegration with the new bone
forming in the SULM. Furthermore, the new bone which osseointegrated with the HA-coated implants has a
possibility to remain for a long time.
