抄録
It is known that hnRNP D0 protein specifically binds to both telomere-sequence DNA and RNA. The hnRNP D0 structure has been determined, and the interactions with the target RNA/DNA have been characterized by NMR. Spatial localization of specific and non-specific interactions with RNA/DNA on the interactive β-sheet surface of hnRNP D0 has been found. It is also found that hnRNP D0 has the ability to transform RNA/DNA quadruplex to a single strand.
