生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
総説
多細胞生物の再帰的増殖と細胞タイプ多様性の両立条件
吉田 寛古澤 力金子 邦彦
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ジャーナル フリー

2007 年 47 巻 1 号 p. 029-035

詳細
抄録
The development of a multicellular organism is a dynamic process. With the increase of the cell number, starting from one or a few cells, cells are differentiated with different compositions. These differet types of cells form an ordered pattern. It is rather surprising that differentiation in cell types and formation of controlled patterns are compatible, because the former gives morphogenetic diversification whereas the latter implies recursive production of a cell ensemble, reducing individual differences. We studied this problem by taking a simple cell model with intracellular reaction dynamics of chemical concentrations, cell-cell interactions, and increase in cell numbers. We show that, by starting from an initial object consisting of both the cell type with diverse chemicals and the differentiated cell type, the recursive production of a multicellular organism with morphogenetic diversity is possible.
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© 2007 by THE BIOPHYSICAL SOCIETY OF JAPAN
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