原腸陥入運動とケモカインシグナル

抄録

Gastrulation is a crucial event at the early embryogenesis in animals. In vertebrates, gastrulation sets presumptive ectoderm, mesoderm, and endoderm cells in position. Furthermore, primary body axes were established through the gastrulation. Although precise analyses of gastrulation movement have revealed how to organize the body plan, many molecular mechanisms still remained to be clarified. Amphibian embryo, especially Xenopus laevis, lies on a lot of information that had been studied for the subject of gastrulation. This review outlines the movement of mesoderm cells in Xenopus, and discusses the role of a chemokine in cell migration during gastrulation.