生物物理
Online ISSN : 1347-4219
Print ISSN : 0582-4052
ISSN-L : 0582-4052
総説
1細胞レオロジー測定:原子間力顕微鏡による細胞レオロジー計測の新手法
岡嶋 孝治水谷 祐輔
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2012 年 52 巻 5 号 p. 230-233

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Living cells are viscoelastic materials, and thus the cell modulus changes with time and frequency. Recent progress in atomic force microscopy (AFM) combined with cell microarray substrates revealed that the number distribution of the complex shear modulus of cells exhibited a log-normal and became narrower with frequency, according to the power-law rheology model. Moreover, it was demonstrated that the force propagation between focal adhesions on the apical and basal cell surfaces could be directly measured using AFM with micropost substrates.
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© 2012 by THE BIOPHYSICAL SOCIETY OF JAPAN
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