抄録
A wide class of dynamical systems exhibit early signals of state transitions, such as increased fluctuations. Here, we show that prefrontal neurons exhibit increased fluctuations in firing prior to switching codes for behavioral goals. We also demonstrated that decreasing the stability of neural network models resulted in increased firing variability before bifurcations. These results suggest that dynamical transitions in neural networks underlie prefrontal functioning, enabling flexible adaptation in ever-changing environments.