解説
胃の中が強い酸性になる仕組み
キーワード:
membrane transport protein,
P-type ATPase,
X-ray crystallography,
bioenergetics,
proton transport,
structural biology
2019 年 59 巻 2 号 p. 073-078
詳細
2019 年 59 巻 2 号 p. 073-078
When we have food intake, pH of the stomach reaches around 1. This highly acidic environment is indispensable for the digestion. Gastric proton pump, H+,K+-ATPase is a membrane protein responsible for the gastric acid secretion. Its crystal structures now reveal how this proton pump extrudes H+ even into the pH 1 environment of the stomach.
