総説
人工RNA複製システムの実験進化による物質から生命への複雑化プロセスの探求
キーワード:
origins of life,
molecular evolution,
parasite,
coevolution,
emergence of diversity,
open-ended evolution
2021 年 61 巻 4 号 p. 240-244
詳細
2021 年 61 巻 4 号 p. 240-244
How can evolution shape a diverse biological world from a lifeless molecular world? In vitro evolution of artificial molecular replication systems is an attractive approach to investigate possible pathways of a simple molecular system developing towards biological complexity. We describe the progress of experimental investigation to test evolvability of molecules from the pioneering Spiegelman’s work to our studies on an artificial RNA replication system. Especially, we found that coevolution with parasitic molecules is a key to extend evolvability for emergence of diversity and continuous evolution.
