Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Notes
Hepatoprotective Activity of the Constituents in Swertia pseudochinensis
Jian-Chen LiLi FengBao-Hui SunTsuyoshi IkedaToshihiro Nohara
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2005 年 28 巻 3 号 p. 534-537

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抄録
A new xanthone derivative was isolated together with other 13 known constituents from a Chinese natural medicine, Swertia pseudochinensis HARA. Their structures were determined based on the spectral and chemical evidences. Furthermore, respective hexane, ethyl acetate, 1-BuOH, MeOH and water extracts of S. pseudochinensis, and purified compounds were respectively evaluated for their hepatoprotective activities against hepatocyte injury induced by CCl4. All the extracts and isolated compounds exhibited significant hepatoprotective activities at a dose showing no hepatoxicity.
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© 2005 The Pharmaceutical Society of Japan
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