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Biological and Pharmaceutical Bulletin
Vol. 29 (2006) No. 6 P 1271-1274




From the leaves of Aspalathus linearis, 24 known compounds and a new one, aspalalinin (25), were isolated. The structures of the compounds were determined mainly based on spectral evidence. The absolute configuration of aspalalinin was presented on the basis of X-ray analysis. Each isolate was assessed for its estrogenic activity by an estrogen ELISA assay. Compounds 12, 15, and 24 showed the estrogenic activity.

Copyright © 2006 The Pharmaceutical Society of Japan

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