Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
Regular Articles
Solubility Testing of Sucrose Esters of Fatty Acids in International Food Additive Specifications
Yukino NagaiSatoko KawanoKenichiro MotodaMasaaki TomidaChiye TatebeKyoko SatoHiroshi Akiyama
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2017 Volume 40 Issue 3 Pages 284-289


We investigated the solubility of 10 samples of sucrose esters of fatty acids (SEFA) products that are commercially available worldwide as food additives (emulsifiers). Although one sample dissolved transparently in both water and ethanol, other samples produced white turbidity and/or precipitates and did not meet the solubility criterion established by the Joint Food and Agriculture Organization of the United Nations (FAO)/WHO Expert Committee on Food Additives (JECFA). When the sample solutions were heated, the solubility in both water and ethanol increased. All of the samples dissolved transparently in ethanol, and dispersed and became white without producing precipitates in water. The present study suggests that the current solubility criterion of the JECFA SEFA specifications needs to be revised.

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© 2017 The Pharmaceutical Society of Japan
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