Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158

This article has now been updated. Please use the final version.

Fecal lipid excretion after consumption of a black tea polyphenol containing beverage.
- Randomized, placebo-controlled, double-blind, crossover study -
Hiroshi Ashigai Yoshimasa TaniguchiMihoko SuzukiEmiko IkeshimaTomoka KanayaKanako ZembutsuShimpei TomitaMika MiyakeIkuo Fukuhara
Author information
JOURNAL FREE ACCESS Advance online publication

Article ID: b15-00662

Details
Abstract

Obesity is a serious medical condition worldwide. Inhibition of lipid absorption is very important in preventing obesity. In a previous study, we found that postprandial elevation of triacylglycerol was suppressed by the intake of black tea polyphenol (BTP). We also reported that BTP caused lipid excretion into feces in an animal study. The present study is a clinical trial that examined lipid excretion.In this randomized, placebo-controlled, double-blind, crossover study, in the first test period participants were asked to drink either a beverage containing 55 mg BTP or a control beverage without BTP 3 times a day for 10 days. After an 11-day interval, for the second test period, they then drank the alternate test beverage 3 times a day for 10 days. During the test periods, the participants were asked to eat meals standardized according to calorie and fat content. Stool samples were obtained during the last 3 days of each test period for fecal lipid measurements. Total lipid excretion increased from 5.51 ± 1.73 to 6.87 ± 1.91 g/3 days after BTP intake in comparison with intake of the control beverage. These results indicated that BTP increased lipid excretion.

Content from these authors
© 2016 The Pharmaceutical Society of Japan
feedback
Top